Author(s): James O Masko
Acute kidney injury (AKI) is defined as a decline in kidney function that occurs within hours and includes both renal damage and impairment. In AKI syndrome the kidney plays an active role in the course of multi-organ dysfunction, rather than a pathological condition of single organ failure. AKI is becoming a more prevalent and dangerous condition showing impact in public health expenses throughout the world. Because there is no effective pharmaceutical therapy that stops the progression of the injury or reverses it after it has occurred due to the multiple pathophysiological pathways, renal replacement therapy is the sole current option for renal patients. Biomarkers are used as a predictor of the diseases in early stage which is crucial.
