Author(s): ziuya H kelly
Rabies is an acute, progressive, and deadly encephalomyelitis that is transmitted most usually by the bite of a rabid animal. It is responsible for an estimated 61,000 human deaths globally. Due to a lack of sensitive laboratory diagnostic procedures, the true disease burden and public health impact of rabies are still underestimated. Rapid rabies diagnosis can aid in the implementation of early infection control and public health measures, as well as the avoidance of unneeded treatment/medical testing and the timely delivery of pre or post-exposure prophylactic vaccination to family members and medical personnel. Human rabies antemortem diagnosis encourages clinicians to try new therapy approaches in some patients, especially after a few cases of human rabies have been documented to survive. Traditional antemortem and postmortem rabies diagnosis methods have significant flaws. Recent technological advancements have resulted in the improvement or development of various diagnostic assays, including methods for detecting rabies viral antigen and antibody, as well as assays for detecting viral nucleic acid and identifying specific biomarkers.Rabies is an acute, progressive, and deadly encephalomyelitis that is transmitted most usually by the bite of a rabid animal. It is responsible for an estimated 61,000 human deaths globally. Due to a lack of sensitive laboratory diagnostic procedures, the true disease burden and public health impact of rabies are still underestimated. Rapid rabies diagnosis can aid in the implementation of early infection control and public health measures, as well as the avoidance of unneeded treatment/medical testing and the timely delivery of pre or post-exposure prophylactic vaccination to family members and medical personnel. Human rabies antemortem diagnosis encourages clinicians to try new therapy approaches in some patients, especially after a few cases of human rabies have been documented to survive. Traditional antemortem and postmortem rabies diagnosis methods have significant flaws. Recent technological advancements have resulted in the improvement or development of various diagnostic assays, including methods for detecting rabies viral antigen and antibody, as well as assays for detecting viral nucleic acid and identifying specific biomarkers.
